Myasthenia Gravis in Pregnancy: Case Series and Review of Literature
Published: 2022-08-25
Page: 118-125
Issue: 2022 - Volume 5 [Issue 1]
Yavana Suriya Venkatesh *
Department of Obstetrics and Gynaecology, Jawaharlal Institute of Post Graduate Medical Education and Research (JIPMER), Puducherry, India.
Murali Subbaiah
Department of Obstetrics and Gynaecology, Jawaharlal Institute of Post Graduate Medical Education and Research (JIPMER), Puducherry, India.
Latha Chaturvedula
Department of Obstetrics and Gynaecology, Jawaharlal Institute of Post Graduate Medical Education and Research (JIPMER), Puducherry, India.
Jayalakshmi Durairaj
Department of Obstetrics and Gynaecology, Jawaharlal Institute of Post Graduate Medical Education and Research (JIPMER), Puducherry, India.
*Author to whom correspondence should be addressed.
Abstract
Myasthenia gravis is a rare autoimmune disorder affecting the neuromuscular junction and is more common in the women during their second or third decade of life. The course of the disease in pregnancy is unpredictable and may aggravate warranting optimal preconceptional counselling, strict adherence to medication, recognition of complications, avoidance of precipitating factors, intensive antepartum and intrapartum care by multi- disciplinary team for successful outcomes and prevention of life-threatening complications. The pregnancy outcomes in patients with myasthenia gravis is discussed in this case series.
Keywords: Myasthenia gravis, pyridostigmine, neostigmine, anticholinesterase inhibitors, thymectomy